33 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... #summary #table ... #nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW Nephrology ... MCW_Nephrology #diuretics ... #pharmacology # ... halflife #comparison #table
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Normal Acid-Base: Low ... Loop and thiazide diuretics ... #Hypokalemia #Differential ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... vomiting) • Low ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... • Euvolemic (Low ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... Workup #Algorithm #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Primary polydipsia), Low ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al, Low ... >20 mEq/24 h - Diuretics ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
of Polyuria - Differential ... a.k.a. osmotic diuresis ... : Conventional diuretics ... • Central Dl (Low ... Diagnosis #Causes #nephrology