20 results
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... #Anemia #Causes ... #Pathophysiology ... Pathology #Treatment #Management ... #Differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... Clinical Features ... demyelination features ... Syndrome #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... • The cardinal features ... than one after symptom ... the underlying pathophysiology ... Syndrome #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... CMV) • Epstein-Barr ... • Improve the symptoms ... hematology #diagnosis #management
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle ... Crises can be precipitated ... The underlying pathophysiology ... of the baseline anaemia ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... worrisome EKG features ... TLS #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... • Pernicious anemia ... collection with EDTA Pathophysiology ... mineralization Symptoms ... pain - Frequent fractures
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... diet/deficiency symptoms ... /other causes • ... Algorithm #diagnosis #management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... infiltration) Differential ... #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... failure Clinical Features ... are not caused ... Sarcoidosis #Diagnosis #Management