27 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
Vasculitis A group ... , small-vessel vasculitis ... , PR3+ 50%, frequently ... vasculitis - MPO ... #Rheumatology
Frequency of ANCA Positivity in Different Conditions
ANCA-Associated Vasculitis
 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
Frequency of ANCA ... , MPO-ANCA 20%, ... 5%, MPO-ANCA 45% ... MPO-ANCA 90%, Often ... PR3 #diagnosis #rheumatology
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
Auto-antibodies and Differential ... Diagnosis MPA ... (MPO) C-ANCA ( ... ANCA Vasculitis ... #Differential #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Vasculitis: • ... polyangiitis - MPO ... Renal-limited vasculitis ... - MPO: 75-80% - ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
myeloperoxidase (MPO-ANCA ... 100 % Commonly MPO-ANCA ... Vasculitis: + MPO-ANCA ... #rheumatology # ... classification
A System for Vasculitides 

#Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Vessel #Size #Classification ... #ANCA #Differential
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA

doi:10.1038/s41572-020-0204-y

#ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... s41572-020-0204-y #ANCA ... #Vasculitis #GPA ... #MPA #Eosinophilic ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... MPO-ANCA (P-ANCA ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm #rheumatology
Break down Vasculitis based on vessel size
#Diagnosis #Rheumatology #Differential #Vasculitis #VesselSize #Small #Medium #Large #Classification
Break down Vasculitis ... size #Diagnosis #Rheumatology ... #Differential # ... Vasculitis #VesselSize ... Medium #Large #Classification
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... basement membrane; ANCA ... #Diagnosis #Rheumatology ... #Differential # ... Medium #Large #Classification