11 results
diagnosis clinical management msk radiology agammaglobulinemia anatomy avascularnecrosis carpi checklist chondrocalcinosis complications cppd ecu encephalopathy endocrinology extensor feedbackloop gh growthhormone
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... excessive bone ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... extrapulmonary cases ... decreased reflexes Pathophysiology ... of bacilli to bone ... Diagnosis: - MRI
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... in subchondral bone ... boggy" joints, esp carpal ... and subcondral bone ... #signs #symptoms
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... possible secondary ossification ... • MRI is more sensitive ... tear (similar symptoms ... marrow edema and bony
Hand X-Ray Anatomy and Interpretation Checklist 1. Soft tissues - Look carefully at the soft tissue over
Bones - All the ... into the hand and wrist ... important to look for signs ... proximal to the carpal ... rheumatological diseases
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
to the scaphoid bone ... vessels that perfuse bone ... - Sickle-cell disease ... ) • Multiple causes ... #symptoms
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... /Symptoms/Findings ... cells in blood and bone ... Agammaglobulinemia #XLinked #pathophysiology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... phosphorous in bones ... Pseudogout #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology
Extensor Carpi Ulnaris (ECU) subluxation The Extensor Carpi Ulnaris (ECU), is the must ulnar of the
metacarpal, the bone ... and joins the bones ... What are the symptoms ... interacts with the bones ... the ECU tendon, MRI
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