29 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... and Screen for HLH ... HLH syndrome 5. ... #Differential #Diagnosis ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... and Screen for HLH ... HLH syndrome 5 ... #Differential #Diagnosis ... #Algorithm #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
) Clinical Features ... IL-2 receptor Diagnostic ... Criteria): Molecular diagnosis ... Lymphohistiocytosis #diagnosis ... #hematology #criteria
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Presentation / Diagnosis ... Diagnosis via genetic ... Hemophagocytosis in bone ... management #treatment #hematology
Abdominal X-Ray Anatomy and Interpretation Checklist
 - Is there bowel dilatation, wall edema or pneumatosis?
 -
Abdominal X-Ray Anatomy ... Check all of the bones ... interpretation #radiology #diagnosis ... #labeled #anatomy ... #clinical
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential Diagnosis ... be used by the bone ... HLH or Adult Onset ... Hematologic Malignancy ... In adults, HLH is
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Difficulty walking Diagnosis ... Hyophosphatasia #hepatology ... #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... #diagnosis #management ... #Dermatology