39 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... Osteomyelitis / ... BrighamChiefs #Bone ... differential #diagnosis #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... severe swelling causes ... septic arthritis & osteomyelitis ... peds #pediatrics #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... -> Osteomyelitis ... hearing loss, nausea ... inner cortical bone ... #Mastoiditis #pathophysiology
Syphilitic gummas in Tertiary syphilis
Tertiary syphilitic gummas may mimic basal cell carcinoma. The gummatous tumors are
treated, in most cases ... vessels, liver, bones ... syphilis #clinical #photo
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Bisphosphonate suppresses bone ... damage weakens the bone ... #differential #causes ... #pathophysiology
Neuropathic Ulcer: Severe diabetes induced neuropathy has resulted in Charcot foot deformity.
This ultimately lead to large
swelling as well as boney ... destruction caused ... by underlying osteomyelitis ... Images #Clinical #Photo ... #Neuropathic #Osteomyelitis
Osteomyelitis of the Finger Secondary to Embedded Ring: Note that broken
end of ring penetrates the skin
Osteomyelitis of ... the level of the bone ... , resulting in osteomyelitis ... Images #Clinical #Photo ... Radiology #HandXRay #Osteomyelitis
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework Bone ... /Joint Causes of ... • Trauma • Osteomyelitis ... Hematoma Venous Causes ... Edema Arterial Causes
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Glycosylation - AGE cause ... Ulcer Formation Osteomyelitis ... - Infection of bone ... formation, and bone ... #DiabeticFoot #pathophysiology