49 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
#MAS #HLH #Hemophagocytic ... Lymphohistiocytosis #Management ... Treatment #Algorithm #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... CD163 staining of bone ... is found in the bone ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... BrighamChiefs #Bone ... differential #diagnosis #causes ... #hematology
Topical Steroids Cheat Sheet

Dr. Steven Chen https://twitter.com/DrStevenTChen

#Topical #Steroids #CheatSheet #Dermatology #Tips #Management #Classes
Steroids #CheatSheet #Dermatology ... #Tips #Management ... #Classes
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Taar #HLH #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Hemophagocytosis in bone ... TheIDtrivia #HLH #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... candidate) - Bone ... or if a primary hematologic ... #Workup #hematology