25 results
diagnosis hematology signs management oncology workup msk algorithm alkaline alp causes joint leukemia liver pain phosphatase ra rheumatology syndrome abnormal
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
in Sickle Cell Disease ... other orthopedic complications ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Most common symptoms ... - Bone symptoms ... ALP #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Weakness, Incr CK • Bone ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries Takayasu's arteritis: - Onset < 40 yrs -
yrs - Cranial symptoms ... IgG4-related disease ... Erdheim-Chester disease ... : - Bone pain ... #Differential #
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... /Complications: ... weight-bear • Arthritic ... msk #diagnosis #pathophysiology ... #signs #symptoms
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Ligament • Bone ... or nerve root Symptoms ... of Joint Disease ... the subchondral bone ... approach #workup #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• softening of bones ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Hypercellular bone ... When present, symptoms ... , signs, and complications ... von Willebrand disease ... Summary #treatment #hematology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms ... #complications
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