29 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... predispose to other orthopedic ... differential #diagnosis #causes ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
, joint, and skin ... • Pustular skin ... dermatoses • Skin ... Rule out other causes ... SAPHO #Syndrome #Rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... • Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology #
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Intra-Articular - Bone ... Ganglion Cyst - Bone ... Epicondylitis - Skin ... Diagnosis #Algorithm #Orthopedics ... #Causes
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework Bone ... thrombophlebitis Skin ... Brittle nails - Skin ... ulcers - Shiny skin ... extremity #msk #physicalexam
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Clinical #SJS #skin
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... marine microbiota & causes ... months temperate zones ... Vibrio #Vulnificus #skin ... rash #cellulitis #dermatology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Orthopedic Emergencies ... Syndrome • Syndrome caused ... event after long bone ... over the involved skin ... area of erythema, skin
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Effusions: - Hematologic ... - Aneurysmal bone ... Knee #Effusions #causes ... diagnosis #msk #physicalexam
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Headaches • Pale skin ... and petechiae Causes ... • Suggested by bone ... Anemia #oncology #hematology