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diagnosis oncology differential anemia management phosphatase algorithm aplastic biliary cholangitis cirrhosis classification disorders elevation gap globulin hodgkins hyophosphatasia leukemia low
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... growth) Alkaline ... - Highest • Bone ... Intestine - Other causes ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... Most cases diagnosed ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... candidate) - Bone ... not required in all ... ITP, unexplained pancytopenia ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Examination: • Skin ... PBC Labs: • Alkaline ... cholangitis #diagnosis #workup ... #hepatology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... produced in the bone ... a hematologic condition ... a decrease in all ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
marrow + pancytopenia ... Headaches • Pale skin ... and petechiae Causes ... • Peripheral Pancytopenia ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... cells - Blood and Bone ... -> AML: Blast crises ... CLL -> Invade Skin ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... involve one, two, or all ... Workup: • Complete ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... of about three cases ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... Castleman disease • AL ... gastric tumors • Hematology ... differential #diagnosis #hematology
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