102 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Highest • Bone ... Intestine - Other causes ... Most common symptoms ... - Bone symptoms ... Diagnosis #Algorithm #hepatology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... pylori test (GI symptoms ... bypass), LFT (liver disease ... candidate) - Bone ... #Workup #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Pain #SickleCell #Disease ... differential #diagnosis #causes ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... Differential #Diagnosis #hematology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... vomiting, auditory symptoms ... • Meniere's Disease ... Media • Temporal Bone ... Imbalance, neurologic symptoms
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... hemorrhagic rash; symptoms ... CNS and hematologic ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Dyspepsia - Signs, Symptoms ... and Pathophysiology ... nonerosive reflux disease ... Functional #Dyspepsia #Pathophysiology ... gastroenterology #symptoms