17 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Osteoporosis: Pathogenesis ... 30 (post-peak bone ... Decr estrogen • Bone ... #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms ... Infertility • Decr Bone ... mineral density and osteoporosis ... sleep apnea, cor pulmonale ... #genetics #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... osteoporosis, Kidney ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... -> Reduced Bone ... Formation, Increased Bone ... #pathophysiology ... #signs #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... infarcts, osteoporosis ... Disease #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Normal CK • Osteoporosis ... Complications #pathophysiology ... #signs #symptoms
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Trauma to the long bone ... Pathophysiology ... onset widespread pulmonary ... #Diagnosis #Signs
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection
 • Dehydration
Short Bowel Syndrome ... Chronic Adverse Signs ... Nephropathy • Bone ... Disease, Osteoporosis ... Ileal #Resection #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... symptoms of active pulmonary ... decreased reflexes Pathophysiology ... of bacilli to bone
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... - CHF - Pulmonary ... #diagnosis #pathophysiology ... #symptoms #signs