10 results
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... /joint pain Psychiatric ... Symptoms: Disorientation ... Secondary #Tertiary #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
cause excessive bone ... formation MSK ... hearing loss #PagetsDisease ... #pathophysiology ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
CTx - marker of bone ... resorption • Lytic bone ... formation #PagetsDisease ... #pathophysiology ... diagnosis #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
and underlying bone ... joint capsule or bone ... Diagnosis #signs #symptoms ... #msk #orthopedics ... #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Mucous membranes • Bone ... • Persons with psychiatric ... musculoskeletal symptoms ... Psychiatric symptoms ... nonimmune hemolysis MSK
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Osteoporosis - Low bone ... mortality rates of all psychiatric ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
hormone levels cause bones ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry