11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... Risks factor for HIV ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... vasculitis - GPA ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: HCV infection, ... HBV infection, ... HIV infection ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... - parvovirus, HIV ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Framework The DDx ... NSAIDs/Aspirin, IV ... • Parasitic infections ... #Diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... - Trauma - Infection ... RA, Sjogren's, GPA ... ITP - APLS - HIT ... deficiency Work
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Calcium oxalate Infectious ... e.g., congenital hip ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... to exclude are infections ... CTD) • ANCA (Dx ... • HBV HCV • ... #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Include: • Viral infections ... (acute HIV, HBV ... gastric tumors • Hematology ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... MPO > PR3 60/ GPA ... drug exposure or Dx ... #Diagnosis #Rheumatology