12 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
infection. ... - parvovirus, HIV ... #rheumatology # ... approach #workup ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... Risks factor for HIV ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Calcium oxalate Infectious ... e.g., congenital hip ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip ... • XR, MRI to dx ... • Differentiate ... diagnosis #causes #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... Weight loss - DDX ... Brucellosis - Viruses: HIV ... Effusions: - Hematologic
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... Parvovirus B19 • HIV ... #pain #Differential ... Diagnosis #MSK #rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Framework The DDx ... NSAIDs/Aspirin, IV ... • Parasitic infections ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... to exclude are infections ... CTD) • ANCA (Dx ... Cryoglobulins • HIV ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... vesicular eruption • Joints ... Palpable purpura, joint ... drug exposure or Dx ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Macrocytic anemia DDX ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology