19 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
: Proximal tubule ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... in the distal tubule ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Defects in Kidney Tubule ... ascending limb Gitelman ... Liddle syndrome ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... , Renal tubular ... #nephrology #management ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Hypokalemia - Differential ... hypokalemia • Renal tubular ... , Gitelman's syndrome ... #hypokalemia #differential ... algorithm #causes #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Hypoperfusion • Hepatorenal ... syndromes • Drugs ... Shock Acute Tubular ... #KidneyInjury #Nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology ... #Differential #
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI - Differential ... calcineurin inhibitors, hepatorenal ... syndrome) • Vascular ... , Lupus Acute Tubular ... #Diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... high in kidney tubular ... urine #Algorithm #nephrology ... #differential #
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Metabolic Alkalosis: Differential ... diuretics after renal tubule ... indicates a renal tubule ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology