1034 results
Budd Chiari Syndrome
Hepatic vein obstruction. Can be caused by thrombosis or sometimes a tumour. Can lead
Budd Chiari Syndrome ... Can be caused by ... or sometimes a tumour ... #Diagnosis #Causes ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... high WBC count cause ... hyperviscosity syndrome ... WBC >100k, + lab signs ... Lysis Syndrome:
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... GHRH hypothalamic tumors ... neuroendocrine tumors ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
conditions (1.5%) : tumors ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Dementia - 2nd cause
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... abdomen for adrenal tumors ... contralateral to the tumor ... #Cushings #Syndrome ... Hypercortisolism #Diagnosis #signs
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Non-Infectious Causes ... disease • Behcet's syndrome ... • Hyper-IgD syndrome ... • Tumor necrosis ... Brucellosis Faget's Sign
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... - Most common tumour ... • Giant Cell Tumour ... #Tumours #MSK # ... #Orthopedics #Causes
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... neurologic symptoms/signs ... Infratentorial Tumors ... Cerebellopontine Angle Tumors ... • Glomus Tumors
Marfan Syndrome - Signs and Symptoms

- Caused by mutations in the fibrillin-1 (FBN1) Gene (chromosome 15)
-
Marfan Syndrome ... - Signs and Symptoms ... - Caused by ... Dominant #Marfans #Syndrome ... #Diagnosis #Signs
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction (Collier's sign ... Pineal region tumors ... → "setting sun sign ... gabifpucci #Parinauds #Syndrome