63 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... allele of RB1 tumor ... allele of RB1 tumor ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pathogenesis and Clinical ... • Pituitary turnors ... adenomas that require treatment ... the pituitary tumor ... Signs / Symptoms
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... Peripheral #Pathology #Microscopy ... #Clinical #Blood
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... to repair => Microscopic ... #orthopedics #pathophysiology ... #symptoms #signs
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
malignant bone tumor ... proximal femur Clinical ... injury • Systemic symptoms
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... ICU transfer • Tumor ... MatthewHoMD #TLS #Tumor
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
patients with minimal tumor ... immunophenotype Clinical ... Splenomegaly 5) Symptoms ... transformation) Treatment ... Constitutional symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... GHRH hypothalamic tumors ... neuroendocrine tumors ... diagnosis #signs #symptoms
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
keratinization, prominent tumor ... carcinoma #Pathology #Clinical ... #Microscopy #Mosaic