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management differential hematology syndrome treatment behcet cancer disease emergencies headache leukemia leukostasis lysis ms multiple myelitis oncologic palsy pathophysiology retinoblastoma
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... allele of RB1 tumor ... mutated in all cells ... pathophysiology #ophthalmology ... #diagnosis #signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... - ACS, AKI, acute ... /- rasburicase Tumor ... rate or large tumor ... #Leukostasis #Tumor
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... EMERGENCIES: Tumor ... Hyperuricemia • Acute ... #differential #diagnosis
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... bleed, abscess, or tumor ... #headache #signs ... #symptoms #clues ... #differential #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Fibrinolysis & DIC • Tumor ... Intracellular Urate, Potassium ... Leukemia #Hematology #Oncology ... #Diagnosis
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... GrepMed Handbook Acute ... ophthalmoplegia), systemic signs ... HIV, Lyme, GBS, tumor ... Imaging (if atypical symptoms
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Forms of MS: • Tumor-like ... Signs and symptoms ... objective evidence of neurologic ... ) • Acute: ... #management #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Enhancement - TM and tumor ... Pleocytosis > 100 cells ... #management #neurology
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