16 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... fractures • Short ... • Obesity -> Type ... #peds #pediatrics
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Clinically significant ... ) Differential ... likelihood of negative clinical ... #differential # ... #pathophysiology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
thrombosis of short ... Clinical manifestations ... Doppler US : halo sign ... efficacy of GCs Abnormal ... Ophthalmology #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... low and appear abnormal ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... workup What type ... - Progressive amnesia ... (parkinsonian signs ... MNCD #Dementia #Differential
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
heart disease, interstitial ... include diabetes, anemia ... Nail #Diseases #Abnormal ... #Pathology #Diagnosis ... #Clinical #Signs
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Albumin ≤3.0 g/dL, anemia ... effusion, or z scores ... and lab signs ( ... #Diagnosis #Peds ... #Pediatrics #Kawasaki
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
capillaries and interstitial ... the Journal of Clinical ... reasoning during clinical ... from accessing port ... #differential #
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... congenital defects) -> Abnormal ... -> Cherry-red spot ... ophthalmology #diagnosis ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Kikuchi disease • Type-I ... • Malar rash - spares ... lymphopenia, low PLT • Anemia