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vasculitis disease patterns behcet cryoglobulinemia cryoglobulins erythematosus laboratory myasthenia rheumatoid signs sjogrens symptoms testing types vasculitides workup
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Juvenile Idiopathic Arthritis ... (SLE), Systemic ... #Antibodies #ANA ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Juvenile Idiopathic Arthritis ... : Lupus (SLE), Systemic ... Arthritis, Sjögren ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... arthritis, adult-onset ... Arthritis: • ... Symptoms limited to: Arthritis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthritis) • ... Types II and III ... (SLE), rheumatoid ... arthritis, Sjögren's ... #types #classification
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
, rheumatoid arthritis ... , SLE Myasthenia ... life-threatening Differential ... #diagnosis #management ... #neurology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic arthritis ... (SLE) - Antinuclear ... of Inflammatory Arthritis ... arthritis (RA) ... of reactive arthritis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
myocarditis, coronary arteritis ... , Reactive arthritis ... Ocular melanoma • Arthritis ... Arthritis, AS Treatment ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... Diagnosis: Systemic ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Arthritis Malignancy ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... GCA (Giant Cell Arteritis ... mucositis • Rash, arthritis ... often causes arthritis ... #Diagnosis #Rheumatology
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