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ana patterns syndrome vasculitis arthritis behcet classification erythematosus fungal gravis infections infectiousdiseases laboratory myasthenia mycoses rheumatic signs sjogrens sle symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
and Associated Rheumatic ... Juvenile Idiopathic Arthritis ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... vasculitis, rheumatoid ... • Type-I Interferonopathies ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... double-stranded DNA antibodies ... Tests for All Types ... ANA and RF (if clinical ... #Disease #Rheumatoid
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... salivary ducts Clinical ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammatory lesions-interstitial ... rheumatic diseases ... purpura: strong sign ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Sjogren syndrome, rheumatoid ... arthritis, SLE ... life-threatening Differential ... - Peek sign ... #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... purpura: Strong sign ... affects the skin, neurologic ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... Inhalation of spores ... Meningitis, septic arthritis ... #Management #Infections
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