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ana patterns vasculitis arthritis behcet classification erythematosus gravis laboratory myasthenia rheumatic signs sjogrens sle symptoms systemic testing vasculitides workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
and Associated Rheumatic ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... #Antibodies #ANA ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... vasculitis, rheumatoid ... • Type-I Interferonopathies ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... salivary ducts Clinical ... Arthralgia and Arthritis ... #Rheumatology # ... Diagnosis #Management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... double-stranded DNA antibodies ... Tests for All Types ... ANA and RF (if clinical ... #Disease #Rheumatoid
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammatory lesions-interstitial ... rheumatic diseases ... purpura: strong sign ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
, rheumatoid arthritis ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... purpura: Strong sign ... affects the skin, neurologic ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
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