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diagnosis management differential ana antinxp2 antinxp2dm arthritis autoimmune dermatology erythematosus fungal infections infectiousdiseases laboratory lupus mycoses myopathy myositis patterns polychondritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... healthy adults, and should ... context of other symptoms ... likely it will be clinically ... , Interstitial Pulmonary
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases Clinical ... Signs/Symptoms: ... decreased reflexes Pathophysiology ... bacilli to bone/joints ... damage - CXR should
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... Syndrome: Fever, joint ... Myositis #Myopathy #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , dermatomyositis ... • Type-I Interferonopathies ... Arthritis: • Joint ... Induced Lupus: • Symptoms
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
erythematosus (SLE) - Antinuclear ... double-stranded DNA antibodies ... Tests for All Types ... ANAs RF test should ... ANA and RF (if clinical
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... , and back and shoulders ... interphalangeal joints ... auricular papules Clinical ... had more severe disease
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... Anti-Matrilin-1 Ab ○ Antibodies ... to type II collagen ... Polychondritis #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... has five major clinical ... muscle aches, joint ... Inhalation of spores ... Aspergillosis Pathophysiology
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