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differential management rheumatology dermatology lupus adultonset hepatology injury liver oncology petechiae petechial sle stills vesicular vesiculobullous activation anemia aosd causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... • Immunologic Workup ... Evolution: Chronic disease ... Lupusreference #druginduced ... #diagnosis #management
Algorithm for Diagnosis of the Vesiculobullous Rash Febrile, Diffuse Distribution: - Varicella, Smallpox, Disseminated, Gonococcal,
Algorithm for Diagnosis ... Purpura Fulminans, DIC ... Hand Foot & Mouth Disease ... #Algorithm #Diagnosis ... #Dermatology #Skin
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Glucocorticoids, IL ... #Algorithm #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... #DrugInduced #Liver ... #Algorithm #hepatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Differential Diaqnoses ... MAS, Visceral, DIC ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... of SLE versus DIL ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... fulminans, or DIC ... hand-foot-and-mouth disease ... #Diagnosis #Dermatology ... #Algorithm #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... thrombocytopenia - DIC ... #Algorithm #workup ... #hematology #testing
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... fulminans - DIC ... deficiency Work ... #Algorithm #Causes
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... maculopapular rash ... synovitis (40%) Treatment ... #AOSD #rheumatology ... #treatment
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