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dermatology differential blood oncology product reactions alopecia anemia causes chronic cll diffuse dress erythematous febrile focal hairloss hyperthermia infections infectiousdiseases
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... Headaches • Pale skin ... recurrent infections/fevers ... Anemia #oncology #hematology ... #diagnosis #management
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... redness of the skin ... syndrome (SSS) ... and toxic shock syndrome ... #Diagnosis #Dermatology
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... loss from the skin ... #Hyperthermia #comparison ... #diagnosis #management
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... • Loose anagen syndrome ... - Secondary to Skin ... Follicularis • Aplasia
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Skin involvement ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Hepatomegaly • Skin ... Pure red cell aplasia ... • Richter’s Syndrome ... workup #oncology #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... other RGM • Plastic ... Hematologic malignancy ... Diagnosis Of NTM
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... due to marrow aplasia ... infections with skin ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... due to marrow aplasia ... infections with skin ... #Transfusions #diagnosis ... #management #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... • Inner ear • Skin ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management
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