13 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... impaired cellular immune ... HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... #Management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... underlying genetic immune ... absent NK cell activity ... #management #treatment ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... (specifically immune ... and M panel Management ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... noncompliance • Clinical ... initiation Clinical ... • Persistently active ... #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... Idiopathic • Infections ... HCV - HIV • Immune ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology: • Immune ... response preceding infection ... Guillain-Barre Clinical ... Can begin in arms ... #management #treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... Erythema nodosum • Immune ... • PET scan - activity ... #oncology #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... increased B-cell activity ... → local immune ... renal failure Clinical ... Pulmonary: dyspnea