11 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
clinical findings ... processes occur in the skin ... dorsum of the hands ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... fingertips ("mechanic’s hands ... auricular papules Clinical ... • Mechanic's hands ... #dermatology #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... #Diagnosis #Clinical ... #Photo #Dermatology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... wane; diagnosis ... trauma leads to skin ... Sporotrichiosis #Infection #clinical ... #photo #hand
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... syndrome (Clinical ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease: Clinical ... Findings Diagnostic ... • Polymorphous rash ... Edema/erythema on hands ... - Generalized Skin
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Vasculitis (LCV) of the Hand ... Diagnosis? ... systemic symptoms ... Vasculitis #LCV #Hand ... #photo
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dog or cat bite. symptoms ... abrupt onset of symptoms ... the key to the diagnosis ... difficult to culture and ... #clinical #photo
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... variably: On one hand ... in literature (NEJM ... required due to skip ... required +/- prompt ophthalmology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... , mucositis • Rash ... • Progressive symptoms ... vasculitis • Behcet