10 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
clinical findings ... processes occur in the skin ... dorsum of the hands ... -> Heliotrope Rash ... Pathophysiology #Signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... fingertips ("mechanic’s hands ... auricular papules Clinical ... • Mechanic's hands ... #dermatology #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... #Diagnosis #Clinical ... #Photo #Dermatology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... #photo #hand
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease: Clinical ... Findings Diagnostic ... Edema/erythema on hands ... & feet Signs ... - Generalized Skin
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... syndrome (Clinical ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Vasculitis (LCV) of the Hand ... Diagnosis? ... systemic symptoms ... Vasculitis #LCV #Hand ... #photo
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology ... #Symptoms #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... vasculitis • Behcet
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... Gottron sign) ... DM • CPK 10X ULN ... • Mechanic's hands