7 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... fingertips ("mechanic’s hands ... auricular papules Clinical ... • Mechanic's hands ... #dermatology #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
(DM) and Polymyositis ... clinical findings ... dorsum of the hands ... -> Heliotrope Rash ... #PM #Diagnosis
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... wane; diagnosis ... trauma leads to skin ... Sporotrichiosis #Infection #clinical ... #photo #hand
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... the palms of the hands ... #Diagnosis #Clinical ... #Photo #Dermatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... (blue-purple) rash ... • Erythematous rash ... auricular papules Clinical
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology ... #GiantCell #arteritis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... DM • CPK 10X ULN ... • Mechanic's hands