10 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... , autoimmune disorder ... negative anti-lgG ... CLL (older) • Autoimmune ... younger pts) Differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... within 1 month of infection ... arthritis - with the skin ... formation, systemic autoimmune ... should have other symptoms
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Vasculitis (LCV) of the Hand ... Differential for ... systemic symptoms ... , foods, autoimmune ... Vasculitis #LCV #Hand
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... arthralgia, arm/leg ... • Progressive symptoms ... purpura (lower legs
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
spinal cord - Autoimmune ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... multiradicular pain - Leg ... #lesions #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... +/- myocardial infarction ... Behcet disease) Differential ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... /Sepsis/Shock, Autoimmune ... Neurological symptoms ... Reversible course Differential ... Diagnosis: • Infection
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... disease • Non-autoimmune ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... vasculitis vs infection ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tenderness → Consider infectious ... ) • Anti-Mi2 (skin ... • Mechanic's hands ... #rheumatology #differential