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differential alkalosis diabeticketoacidosis algorithm aniongap chloride diabetes edka endocrinology gitelman heat heatstroke hypokalemia illness insulin ketoacidosis management stroke symptoms syndrome
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... Polyphagia • Polyuria ... #pathophysiology
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... with anorexia, vomiting ... significant anion gap metabolic ... Common, early signs ... , vomiting, abdominal
Typical Clinical Features of DKA: - Acetone breath - Tachycardia - Soft Bp
/vomifing - Abdominal ... pain - Polyuria ... #Diagnosis # ... Diabetic #Ketoacidosis ... #Signs
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Gastrointestinal: Vomiting ... acidosis • Diabetic ... the indicated causes ... of sodium and potassium ... #differential #diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... : Differential Diagnosis ... Gastric alkalosis: vomiting ... other • Severe potassium ... #Causes #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Loss of sodium/Potassium ... • Labs: - Metabolic ... Collapse: • Pathophysiology ... → Syncope • Signs ... , Vomiting, Diarrhea
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypochloremic metabolic ... Surreptitious vomiting ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
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