16 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... Most cases diagnosed ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
cases there are ... splenomegaly, abnormal neurology ... , back pain Haematology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... vomiting, abdominal pain ... ) Differential Diagnosis ... Maternal Support - Critical ... Liver #Pregnancy #hepatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... myasthenia Diagnosis ... Myasthenia Crises ... Myasthenia #Gravis #diagnosis ... #management #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Summary Causes ... Dermatomyositis Clinical ... nephrotoxicity to kidney ... #Management #causes
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
: • Based on clinical ... More likely to cause ... in myasthenic crisis ... - Improves clinical ... #management #neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
(SRC) Clinical ... : 1) Acute kidney ... , add other BP meds ... • Refractory cases ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... may precede the neurologic ... the underlying cause ... until cause identified ... #management #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Clinical ... Hands or feet • Pain ... #management #treatment ... #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... Heart, lung, and kidney ... tests ↑ AST ↑ ALT ... Activation #Syndrome #Diagnosis ... #Management #Hematology