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neurology rheumatology myasthenia syndrome workup anesthesiology antinxp2 antinxp2dm capillary causes checklist clarksons crisis dermatology dermatomyositis differential encephalopathy endocrinology hyperthermia hyperthyroidism
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Neck: “dropping ... myasthenia Diagnosis ... and EMG Findings ... stimulation - Single fiber ... #diagnosis #management
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism Overview Clinical ... Hyperdefecation • Anterior neck ... diffuse goiter (Graves ... antibodies (TRAb) if Graves ... ' disease is suspected
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... : • Based on clinical ... - Improves clinical ... #Myasthenia #Gravis ... #diagnosis #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... Systemic (head and neck ... IgG4 #Related #Disease ... #diagnosis #management
Lyme Disease - Diagnosis and Management Summary Lyme Disease Epidemiology: - Spirochete - Reservoir: small mammals & birds - Transmitted
Lyme Disease - Diagnosis ... and Management ... Clinical Progression ... Headache/stiff neck ... #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... axillae and anterior neck ... , invasive BP, CVP ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
by 24 hours or longer ... Shock, Autoimmune disease ... epilepticus Treatment ... underlying cause • Treatment ... #management #neurology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... tissues: Myalgia, paresthesia ... ) • IVIg 2 g/kg ... leak #syndrome #diagnosis ... #management #timeline
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... auricular papules Clinical ... had more severe disease ... positive patients Treatment ... #management #rheumatology
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