10 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
AST/ALT (5-10x ULN ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Maternal Support - Critical ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... and hepatorenal syndrome ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... hepatopulmonary #syndrome ... #treatment #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... diseases and hepatitis ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
enzymes (2x ULN ... doubling of Cr), pulmonary ... patients • HELLP: Syndrome ... diagnosis so have high clinical ... obstetrics #cardiology #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... , INC risk PE, Pulmonary ... vasculitis: 10%-16% Liver ... • Autoimmune hepatitis ... Rheumatology #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... #Differential # ... Diagnosis #Management