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diagnosis nephrology differential algorithm nephrotic hyponatremia management glomerulonephritis hematuria treatment urology blood classification rheumatology syndromes testing acute aki albuminuria amyloid
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... #Nephrotic #Syndromes
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... /nephritic syndromes ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... bleeding (proteinuria ... for renal biopsy ... if cause not identified
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... #urology #nephrology ... #renal #urine #
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... • Drugs Glomerular ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... Interstitial nephritis ... syndrome: troponin ... #causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #proteinuria #nephrotic ... #syndrome #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Serum or urine for ... infections are common causes ... #testing #workup ... #nephritic #nephrology
Albuminuria (Grades) and Risk for CKD Normal to mildly increased albuminuria: - Albumin excretion rate: < 30
associated with worse renal ... Nephrotic-range ... Urine total protein ... syndrome ... classification #CKD #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Causes of Hyponatremia ... > 20: • Renal ... < 20 • Nephrotic ... Diagnosis #Algorithm #Causes ... #nephrology
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