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Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... Confirmatory test ↑Se ... A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... +++ (Plt, Hb), Hepatic ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management