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management differential druginduced sle table activation antimda5 antimda5dm autoimmune connectivetissuediseases cppd ctild degenerative dermatology dermatomyositis dil erythematosus gout hematology inflammatory
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
RA: rheumatoid arthritis ... SLE : systemic lupus ... ConnectiveTissueDiseases #ILD ... #Differential #Comparison ... #Associations
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Prognosis: Usually mild ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... joints (shoulders, wrists ... #CPPD #Gout #Comparison ... #rheumatology # ... Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... pain • Swan neck/Ulnar ... Erythematosus #Diagnosis ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
-74%] • Blood tests ... frequently described Association ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
in Rheumatoid arthritis ... , Lupus, etc) -> ... cartilage triggers a mild ... #Degenerative #Comparison ... JointDisease #JointPain #Diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... Prognosis: Usually mild ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... (also seen in association ... • Nonerosive arthritis
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