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diagnosis differential management lupus signs ana antibodies antinuclear behcet classification comparison druginduced erythematosus joint monoarthritis monoarticular msk myopathy myositis oligoarthritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... Juvenile Idiopathic Arthritis ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... : SLE, Reactive ... management #signs #symptoms ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
constitutional symptoms ... Rheumatologic Disease ... • SLE • Psoriatic ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... pain • Swan neck/Ulnar ... Induced Lupus: • Symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... Joint diseases ... boggy" joints, esp carpal ... Boutonniere's ulnar ... pathophysiology #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... constitutional symptoms ... Evolution: Chronic disease ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Presentation - Systemic Symptoms ... retinopathy Lab Tests ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Diagnostic Tests ... RP-ILD), dermato-rheumatologic ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... ethnicities Symptoms ... cases such as: • SLE ... Diagnosis: • Clinical tests ... Polychondritis #rheumatology
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