14 results
Bilirubin Metabolism - Pathophysiology
 • Conjugated Bilirubin
 • Unconjugated Bilirubin

By Dr. Khushboo Gala @LouLectures

#Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... - Pathophysiology ... Bilirubin • Unconjugated ... #Bilirubin #Metabolism ... #hepatology #Liver
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... cytochromes) • Unconjugated ... Tests #Laboratory #Metabolism ... Bilirubin #Hepatology #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
(MALA) Pathophysiology ... cycle found in the liver ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Clearance: Systemic liver ... Inborn Errors of Metabolism ... Presents as AG acidosis ... Differential #Diagnosis #criticalcare
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
impairment of cellular metabolism ... sweat) - its metabolism ... glucose by the liver ... perfusion - shock->treatments ... before beginning treatment
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
• Labs: - Metabolic ... acidosis - Rhabdomyolysis ... - AKI - Liver ... Collapse: • Pathophysiology ... - Mild lactic acidosis
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... stores in the liver ... beta-oxidation in the liver ... The metabolism of ... #criticalcare #
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
Aka pyroglutamic acidosis ... Inborn errors of metabolism ... deficiency) • Liver ... organic acid screen Treatment ... diagnosis #management #treatment
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal: metabolic ... acidosis, oliguria ... AI, thyroid dz liver ... management #Overview #criticalcare
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal: metabolic ... acidosis, oliguria ... AI, thyroid dz liver ... management #Overview #criticalcare