234 results
Bilirubin Metabolism - Pathophysiology
 • Conjugated Bilirubin
 • Unconjugated Bilirubin

By Dr. Khushboo Gala @LouLectures

#Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... Pathophysiology • Conjugated ... Bilirubin • Unconjugated ... #Bilirubin #Metabolism
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... → Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... #Biochemistry #Metabolism
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
route of APAP metabolism ... formation of the toxic metabolite ... conjugate the toxic metabolite ... routes of liver metabolism ... #Pathophys #Toxicology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... during hypoxic metabolism ... salicylate toxicity causes ... #Anion #Gap #Metabolic
Causes of Rhabdomyolysis - Differential Diagnosis
 • Drugs & Toxins (Statins, alcohol, cocaine)
 • Direct Muscle
Causes of Rhabdomyolysis ... (myositis) • Metabolic ... enzymes or lipid metabolism ... Differential #Diagnosis #Causes
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Pathophysiology #Toxicology ... EthyleneGlycol #Metabolism
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... LacticAcidosis #Toxicity #Toxicology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... Tests #Laboratory #Metabolism
Metabolism of Albumin and Causes of Hypoalbuminemia 

#Albumin #Hypoalbuminemia #Metabolism #Causes #pathophysiology
Metabolism of Albumin ... and Causes of Hypoalbuminemia ... Hypoalbuminemia #Metabolism ... #Causes #pathophysiology
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism