51 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... Reticulocytes • Iron ... Reticulocytes, Increased Unconjugated ... Disorder • RBC Metabolism ... Diagnosis #Algorithm #Causes
High Anion Gap Metabolic Acidosis (HAGMA) - Mnemonics
Why should we switch from MUDPILES to GOLDMARK?
 •
High Anion Gap Metabolic ... • Metabolic acidosis ... • Iron and isoniazid ... toxins that can cause ... #AnionGap #Metabolic
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
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Acute Iron Poisoning ... Abdominal pain, nausea ... deterioration Shock and metabolic ... - Anion gap metabolic ... Poisoning #Toxicity #Toxicology
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Others: Hemolysis, Iron ... metabolism disorders ... @drkeithsiau #Iron ... #Deficiency #Causes
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Causes of Apparent ... Myocarditis Metabolic ... Inborn Errors of Metabolism ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
autosomal recessive metabolic ... critical for the metabolism ... and gut, which causes ... #clincial #peds
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
can cause an anion ... gap metabolic acidosis ... Ill Shock and metabolic ... acidosis • Metabolic ... #Toxicity #Toxicology
Toxic Alcohol Metabolism and Metabolites

#Toxic #Alcohol #Metabolism #Metabolites #Toxicology #Pharmacology
Toxic Alcohol Metabolism ... Toxic #Alcohol #Metabolism ... #Metabolites #Toxicology ... #Pharmacology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... angioedema) • Metabolism ... amount of hepatic metabolism ... : Urine Common Uses ... #Indications #Pharmacology