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diagnosis differential approach vasculitis workup autoimmune classification comparison degenerative gout inflammatory jointdisease jointpain management myopathy myositis pathophysiology treatment vasculitides versus
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Adjacent bursa • Tendon ... both at rest and ... -60 minutes or longer ... e.g., congenital hip ... #Pain #MSK #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... warm, swollen, tender ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain ... in Rheumatoid arthritis ... tend to bear the ... affects the knee hip ... Comparison #Versus #MSK
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... diminished, or tender ... retinopathy Lab Tests ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diminished, or tender ... of shoulder and hip ... vesicular eruption • Joints ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... ankles, knees, fingers ... frequent attacks • Arthritis ... elbows, Achilles tendon ... management #treatment #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... Syndrome: Fever, joint ... weakness + atrophy- Hip ... flexors, quadriceps, finger ... • Nonerosive arthritis
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