53 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... revealed 25% plasma cells ... stain) #Clinical #HONC ... Leukemia #Smear #NEJM
Cells, Molecules, and Therapies. Shown is a simplified schematic depiction of major cell types within white-matter
Cells, Molecules ... depiction of major cell ... #Pathophys #Neuro ... DiseaseModifying #Targets #NEJM
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
DNA Repair in Breast ... common feature of breast ... cancer #Pathophys #Honc ... BreastCancer #DNARepair #NEJM
Nystagmus from Wernicke’s Encephalopathy - Magnetic resonance imaging of the brain showed T2 hyperintensities involving the
#Clinical #Radiology ... #Neuro #Wernicke ... MRI #Thalamus #NEJM
Creutzfeldt-Jakob Disease - Magnetic resonance imaging (MRI) revealed hyperintensity of the cortical gyri of the frontal
#Clinical #Neuro ... #Radiology #MRI ... CreutzfeldJakob #NEJM
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
of a normal red cell ... spleen in which red cells ... between endothelial cells ... Pathophysiology #Honc ... HereditarySpherocytosis #NEJM
High Attenuation pattern 
1. Chronic eosinophilic pneumonia with peripheral areas of ground glass opacity.
2. Sarcoid end-stage
with peripheral areas ... presenting as areas ... with peripheral areas ... Broncho-alveolar cell ... consolidation #Clinical #Radiology
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
pnuemonitis, as well ... response to cancer cell ... Clinical #Diagnosis #Radiology ... #Honc #CheckpointInhibitors
Squamous-Cell Carcinoma of the Penis with Human Papillomavirus #Clinical #Derm #Honc #Penile #SCC #Glans #HPV #NEJM
Squamous-Cell Carcinoma ... Clinical #Derm #Honc ... SCC #Glans #HPV #NEJM
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer #EBM #Honc #Alectinib #Crizotinib #ALK #ALKPositive #NSCLC
ALK-Positive Non–Small-Cell ... Lung Cancer #EBM #Honc ... VisualAbstract #NEJM