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diagnosis management alkalosis differential hypokalemia icucard metabolic neurology person stiff treatment urinary urine
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... alkalosis • Normal or low ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... alkalosis • Normal/low ... , Gitelman syndrome ... #urine #Algorithm ... #nephrology #differential
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Pathophysiology ... diaphoresis, high HR ... antibody that works ... others (botox, sodium
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
(CrU * volume)/CrS ... 0.6*Wt Required Sodium ... FE Urea 20-70 ... Distress Syndrome ... -2min Calcium chloride
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