20 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... prevalence of 1- ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... ADH promotes Urea ... water retention 1) ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... • nephrotic syndrome ... Diagnosis #Workup #Algorithm ... #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... 1) Check Urine ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #nephrology #sodium
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Diagnosis Algorithm ... treat underlying cause ... cirrhosis, nephrotic syndrome ... #diagnosis #nephrology ... #sodium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... , Gitelman Syndrome ... Volume Expanded - 1° ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... acidosis (type 1 ... , Gitelman's syndrome ... differential #diagnosis #algorithm ... #causes #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
restriction: • Restrict 1 ... volume overload Urea ... promoting passive sodium ... SIADH #Management #hyponatremia ... #nephrology #treatment
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... +K / serum Na >1 ... Cirrhosis, Nephrotic syndrome ... #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... 1) Is it hypotonic ... demyelination syndrome ... Treatment #management #nephrology ... #sodium