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diagnosis differential management alkalosis hypernatremia hypochloremia hypokalemia icucard neurology person sps stiff treatment urinary urine
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... , Gitelman syndrome ... the excretion of sodium ... #urine #Algorithm ... #nephrology #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... • Gitelman's syndrome ... #nephrology #management ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... • Fatigue Chloride ... #Pathophysiology ... #Nephrology #Chloride
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Diagnosis and Workup ... Repeat the sodium ... administration Step 3. ... • nephrotic syndrome ... #Algorithm #Nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic ... History: - Age >3 ... #Syndrome #Diagnosis ... #Workup #nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
-50, Females 2-3 ... Pathophysiology ... (positive in 2/3 ... antibody that works ... others (botox, sodium
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
0.6*Wt Required Sodium ... FE Urea 20-70 ... Fractional Excretion of Urea ... Distress Syndrome ... -2min Calcium chloride
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