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Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology ... of hypotonic hyponatremia ... #hyponatremia # ... nephrology #algorithm ... #Pathophysiology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... Urologic irrigants Hypotonic ... Cirrhosis, Nephrotic syndrome ... #Algorithm #diagnosis ... #sodium #nephrology
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg)
Assess Volume Status,
Hypo-osmolar Hypotonic ... HypoNatremia Algorithm ... #Algorithm #Diagnosis ... #Nephrology #Differential ... #Hypotonic
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... from Bartter syndrome ... krithicism #Gitelman ... #Algorithm #nephrology
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... - Diagnostic Algorithm ... #Hyponatremia #Algorithm ... #Pathophysiology ... #Differential #Nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Algorithm Isotonic ... , Recent TURP Hypotonic ... Cirrhosis, Nephrotic Syndrome ... #Differential #Algorithm ... diagnosis #causes #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Hyponatremia The ... hyponatremia, give ... normal volume-based algorithm ... Cirrhosis, Nephrotic syndrome ... table #sodium #nephrology
Hyponatremia with Severe Symptoms - Management Algorithm with Hypertonic Saline
The goal of acute management is to
Hyponatremia with ... Symptoms - Management Algorithm ... with Hypertonic ... #treatment #Hypertonic ... #Saline #nephrology