23 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Goal correction ... Demyelination Syndrome ... #rate #management ... #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
Rate of Correction ... of Hypernatremia ... evidence that rapid correction ... #Rapid #Rate #Correction ... #Nephrology #Management
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
(max rate of correction ... /L/day) Rapid correction ... demyelination syndrome ... Diagnosis #Treatment #management ... #nephrology #sodium
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... The target for correction ... FE Urate post correction ... Wilkinsonjonny #Hyponatremia ... #Management #algorithm
The Urine / Plasma Electrolyte Ratio - Guide to Fluid Restriction in Hyponatremia
 • U/P Ratio
Restriction in Hyponatremia ... + Medication (Urea ... #Restriction #Hyponatremia ... #diagnosis #management ... #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - ... • Rapid correction ... maximum rate of correction ... Diagnosis #Treatment #management ... #nephrology #sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... volume overload Urea ... into ammonium by urease-producing ... #hyponatremia # ... nephrology #treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology