14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- Blood & BM • ... • Cytopenia -> BM ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... Intracellular Urate
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
less than 200 cells ... recovery (CD4-cell ... enhancement on CT ... periventricular areas ... effect/Edema • EBV
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
HAV, HCV, HEV, EBV ... Infiltration- often breast ... CA, small cell ... Trauma: Shock liver
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
Anaplastic large cell ... tissue, lungs, liver ... ) • BM involvement ... subtle • Small cell ... pattern: mimics NS
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
HBV, HCV, HEV, EBV ... Infiltration: Often breast ... CA, small cell ... fibrosis, Sickle cell ... intestines, white blood cells
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
and vomiting as well ... Clinical #Derm #EM ... #Pneumatosis #CT ... #NEJM
Echinococcal Cysts in the Liver- The physical examination revealed hepatomegaly with a palpable hepatic mass. Laboratory
Echinococcal Cysts in the Liver ... a normal white-cell ... right lobe of the liver ... #clinical #NEJM ... hepatic #radiology #CT
Vibrio vulnificus Infection- At the time of presentation, hemorrhagic bullae measuring 3.5 by 4.5 cm had
contaminated seawater, as well ... including chronic liver ... #clinical #photo ... #NEJM #vibrio #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... disease • Liver ... - gastric and breast ... Chest CT: • Ground-glass
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
chest pain (LR + NS ... Total white blood cell ... Uremia (blood urea ... count < 4,000 cells ... radiograph or CT